Heterocyclic compound - Otsuka Pharmaceutical Co., Ltd.

Title:

Heterocyclic compound

Document Type and Number:

Japanese Patent JP5973994

Kind Code:

B2

Abstract:

A heterocyclic compound represented by the general formula (1) or a salt thereof:wherein m, l, and n respectively represent an integer of 1 or 2; X represents —O— or —CH2—;R1 represents hydrogen, a lower alkyl group, a hydroxy-lower alkyl group, a protecting group, or a tri-lower alkylsilyloxy-lower alkyl group;R2 and R3, which are the same or different, each independently represent hydrogen or a lower alkyl group; or R2 and R3 are bonded to form a cyclo-C3-C8 alkyl group; andR4 represents an aromatic group or a heterocyclic group, whereinthe aromatic or heterocyclic group may have one or more arbitrary substituent(s).

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Inventors:

Nobuaki Ito
Hirofumi Sasaki
Kuninori Tai
Yuichi Shinohara

Application Number:

JP2013511445A

Publication Date:

August 23, 2016

Filing Date:

September 12, 2011

Export Citation:

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Assignee:

Otsuka Pharmaceutical Co., Ltd.

International Classes:

C07D241/38; A61K31/498; A61K31/4985; A61K31/501; A61K31/506; A61K31/517; A61K31/5377; A61K31/538; A61K31/55; A61K31/551; A61K31/5513; A61K31/695; A61P1/00; A61P3/04; A61P5/00; A61P5/14; A61P5/18; A61P9/00; A61P9/04; A61P9/06; A61P9/12; A61P11/00; A61P11/06; A61P13/02; A61P15/08; A61P15/10; A61P17/04; A61P21/00; A61P25/06; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P25/32; A61P25/34; A61P25/36; A61P29/00; A61P43/00; C07D241/44; C07D243/10; C07D401/04; C07D403/04; C07D405/04; C07D409/04; C07D413/04; C07D417/04; C07D471/04; C07D491/048; C07D495/04; C07F7/10; C07F7/18

Domestic Patent References:

JP2010501540A
JP2010500368A
JP2006514987A
JP2002544158A
JP9505035A
JP2000026385A
JP2000500775A
JP6049074A
JP2012528871A

Foreign References:

WO2011068171A1
WO2009061879A1
SU390091A

Other References:

Pharmaceutical Chemistry Journal,1975年,9(6),360-362
Journal of Medicinal Chemistry,2009年,52,4951-4954
Bioorganic & Medicinal Chemistry,2007年,15,2334-2345
Il Farmaco,2003年,58,477-487

Attorney, Agent or Firm:

Asamura patent office

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