Title:
複素環化合物
Document Type and Number:
Japanese Patent JP6653319
Kind Code:
B2
Abstract:
The present invention provides a compound having an MAGL inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, traumatic brain injury, glaucoma, multiple sclerosis etc.), anxiety disorder, pains (e.g., inflammatory pain, cancerous pain, neurogenic pain etc.), epilepsy, depression and the like. The present invention relates a compound represented by the formula (I):
wherein each symbol is as described in the specification, or a salt thereof.
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Inventors:
Shuhei Ikeda
Ryuki Koike
Meeting Junpei Ta
Makoto Fushimi
Kusumoto Tomokazu
Hideyuki Sugiyama
Miya Saki Masako
Hidekazu Tokuhara
Yasushi Hattori
Shin Kamada
Ryuki Koike
Meeting Junpei Ta
Makoto Fushimi
Kusumoto Tomokazu
Hideyuki Sugiyama
Miya Saki Masako
Hidekazu Tokuhara
Yasushi Hattori
Shin Kamada
Application Number:
JP2017510027A
Publication Date:
February 26, 2020
Filing Date:
March 29, 2016
Export Citation:
Assignee:
Takeda GmbH
International Classes:
C07D401/06; A61K31/454; A61K31/4709; A61K31/538; A61K31/5383; A61P21/00; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/22; A61P25/24; A61P25/28; A61P43/00; C07D413/06; C07D413/14; C07D417/14; C07D471/04; C07D491/052; C07D498/04
Domestic Patent References:
| JP2012524810A | ||||
| JP2012524800A | ||||
| JP2013536852A |
Foreign References:
| WO2001064676A2 | ||||
| WO2011058766A1 |
Attorney, Agent or Firm:
Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Junzo Koike
Hirofumi Toma
Atsuko Akai
Tomiya Tozaki
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Junzo Koike
Hirofumi Toma
Atsuko Akai
Tomiya Tozaki