Title:
高解像度のDNA検出の方法および装置
Document Type and Number:
Japanese Patent JP4555484
Kind Code:
B2
Abstract:
The present invention provides methods and devices for detecting a target nucleic acid molecule. A set of oligonucleotide probes integrated into an electric circuit, where the oligonucleotide probes are positioned such that they cannot come into contact with one another, are contacted with a sample. If the sample contains a target nucleic acid molecule, one which has sequences complimentary to both probes, the target nucleic acid molecule can bridge the gap between the probes. The resulting bridge can then carry electrical current between the two probes, indicating the presence of the target nucleic acid molecule.
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Inventors:
Connolly Dennis Michael
Application Number:
JP2000609614A
Publication Date:
September 29, 2010
Filing Date:
April 07, 2000
Export Citation:
Assignee:
Connolly Dennis Michael
International Classes:
C12N15/09; G01N33/53; C12M1/00; C12M1/34; C12Q1/25; C12Q1/37; C12Q1/68; C12Q1/6816; C12Q1/6825; C12Q1/689; G01N33/569; G01N37/00; H01L51/30; C12Q1/70; C40B40/06; G01N1/02
Foreign References:
| WO1999060165A1 |
Other References:
Nature. 1999 Apr 1,Vol.398, No.6726, p.407-410
Nature. 1998 Feb, Vol.391, No.6669, p.775-778
Nature. 1998 Feb, Vol.391, No.6669, p.775-778
Attorney, Agent or Firm:
Hatsushi Shimizu