Title:
How to judge the tendency of calcification
Document Type and Number:
Japanese Patent JP6104265
Kind Code:
B2
Abstract:
The present invention relates to a method for determining the propensity of a fluid for calcification characterized by the following steps:
(i) adding a soluble calcium salt and a soluble phosphate salt to a sample of said fluid;
(ii) incubating said sample at conditions allowing the formation of calciprotein particles (CPPs); and
(iii) determining one or more of the following:
(a) the rate of the formation of primary and/or secondary CPPs;
(b) the amount of primary and/or secondary CPPs; and/or
(c) the rate of the transition of primary CPPs into secondary CPPs,
wherein an increase in one or more of (a), (b) and/or (c) of step (iii) indicates an increased propensity of said fluid for calcification.
Inventors:
Janen-Descent Wilhelm
Pash Andreas
Faleste Stefan
Greber Steffen
Pash Andreas
Faleste Stefan
Greber Steffen
Application Number:
JP2014539362A
Publication Date:
March 29, 2017
Filing Date:
November 07, 2012
Export Citation:
Assignee:
RHEINISCH-WESTFALISCHE TECHNISCHE HOCHSCHULE AACHEN
International Classes:
G01N33/68; G01N21/82; G01N33/483; G01N33/84
Domestic Patent References:
| JP2002139501A | ||||
| JP9072891A | ||||
| JP2003519183A |
Foreign References:
| WO2001049295A1 |
Other References:
JAHNEN-DECHENT WILLI,CIRCULATION RESEARCH,2011年 6月10日,V108 N12,P1494-1509
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto