Title:
サイトカインの免疫原性を減らし、細胞表面マーカーを除去する方法
Document Type and Number:
Japanese Patent JP2008538921
Kind Code:
A
Abstract:
The present invention provides means to assess the comparative allergenicity of proteases. In particular, the present invention provides means to qualitatively assess the potential for any protease to induce an allergic response in humans. In addition, the present invention provides means to select proteases with reduced allergenicity for use in various applications.
Inventors:
Harding, Fiona A.
Application Number:
JP2008508992A
Publication Date:
November 13, 2008
Filing Date:
April 24, 2006
Export Citation:
Assignee:
Genenco International Inc.
International Classes:
C12P21/06; C12N5/07; C12N5/0783; C12Q1/02; C12Q1/37; C07K14/52
Foreign References:
| WO2003073068A2 | 2003-09-04 | |||
| WO2003104263A2 | 2003-12-18 | |||
| WO2002077187A2 | 2002-10-03 | |||
| US6232088B1 | 2001-05-15 |
Other References:
JPN6012011150; Ｅｕｒ． Ｊ． Ｉｍｍｕｎｏｌ． （２００１） ｖｏｌ．３１， ｎｏ．４， ｐ．１２１１-１２１６
JPN7012000789; Ｊ． Ｉｍｍｕｎｏｌ． （２００１） ｖｏｌ．１６７， ｎｏ．２， ｐ．１０１４-１０２１
JPN6012011152; Ｂｉｏｃｈｅｍ． Ｂｉｏｐｈｙｓ． Ｒｅｓ． Ｃｏｍｍｕｎ． （１９９７） ｖｏｌ．２３６， ｎｏ．２， ｐ．５２２-５２６
JPN7012000789; Ｊ． Ｉｍｍｕｎｏｌ． （２００１） ｖｏｌ．１６７， ｎｏ．２， ｐ．１０１４-１０２１
JPN6012011152; Ｂｉｏｃｈｅｍ． Ｂｉｏｐｈｙｓ． Ｒｅｓ． Ｃｏｍｍｕｎ． （１９９７） ｖｏｌ．２３６， ｎｏ．２， ｐ．５２２-５２６
Attorney, Agent or Firm:
Yuzo Yamazaki
Naoto Sugiyama
Shirogane Expo
Toshiaki Akamatsu
Okuko Masako
Ichiro Tasaka
Ono Wataru
Shun Hosaka
Tadao Naito
Naoto Sugiyama
Shirogane Expo
Toshiaki Akamatsu
Okuko Masako
Ichiro Tasaka
Ono Wataru
Shun Hosaka
Tadao Naito