Title:
ネットワーク・システムにおける接続性を解明するための、複数の撹乱の使用法
Document Type and Number:
Japanese Patent JP2007507047
Kind Code:
A
Abstract:
One embodiment of the invention is a method of analyzing the effects of combined perturbers of a network system by means of a set of model predictions for various network configurations, using a set of phenomenologically-based combination surface models. This method can be used to predict the effects of combined perturbers of known networks, for example, providing mechanistic validation for therapeutic compounds. Alternatively, this method can provide constraints for constructing connectivity models from observed combination effects on networks of unknown structure, thus, for example, providing the required understanding to identify novel targets for therapeutic compounds.
Inventors:
Lehar Joseph
Molner Raymond A.
Keith Curtis Tee.
Zimmerman Grant
Molner Raymond A.
Keith Curtis Tee.
Zimmerman Grant
Application Number:
JP2006528330A
Publication Date:
March 22, 2007
Filing Date:
September 27, 2004
Export Citation:
Assignee:
Combinat Rx Incorporated
International Classes:
G01N33/48; G01N33/50; G06F13/00; G06F17/30; G06F19/00; G06G7/48; G06G7/58; G16B5/00
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi