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Title:
ヒト由来のグリコサミノグリカンスルホトランスフェラーゼのポリペプチド及びそれをコードするDNA
Document Type and Number:
Japanese Patent JP4571242
Kind Code:
B2
Abstract:
A polypeptide of glycosaminoglycan sulfotransferase originating from human and having the following physical and chemical properties: (i) action: sulfate group is transferred from a sulfate group donor to N-acetylgalactosamine residue or galactose residue of glycosaminoglycan; (ii) substrate specificity: sulfate group is transferred to the hydroxyl group position at C-6 of N-acetylgalactosamine residue of chondroitin; and sulfate group is transferred to the hydroxyl group position at C-6 of galactose residue of keratan sulfate; and (iii) molecular weight: about from 50,000 to 55,000 Da.

Inventors:
Habuchi
Masakazu Fukuda
Application Number:
JP19506396A
Publication Date:
October 27, 2010
Filing Date:
July 24, 1996
Export Citation:
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Assignee:
Seikagaku Corporation
International Classes:
C12N9/10; C12N15/09; C12N1/21; C12N5/10; C12N15/54; A61K38/00; A61K48/00; C12R1/19; C12R1/91
Other References:
J. Biol. Chem.(1986),Vol.261,No.10,p.4460-4469
J. Biol. Chem.(1995),Vol.270,No.31,p.18575-18580
糖鎖遺伝子とその生物機能 平成7年度科学研究費補助金重点領域研究 研究成果報告書平成5年度-平成8年度(受入日1996.7.2),p.40-41
Biochim Biophys Acta.(1998),Vol.1399,No.1,p.57-61
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Hidemi Matsukura
Tsutomu Toyama