Title:
HUMAN LYMPHOTOXIN DERIVATIVE
Document Type and Number:
Japanese Patent JPH0380082
Kind Code:
A
Abstract:
NEW MATERIAL:A human lymphotoxin derivative of the formula (R is Met or H; X is Ala, Ile or Arg).
USE: An antitumor agent.
PREPARATION: A specific region of the N-terminal of human lymphotoxin is artificially deleted and the amino acid residue of the remaining N-terminal is modified by a genetic operation means.
Inventors:
UESUGI HARUICHI
TAKEDA TAKESHI
TAKEDA TAKESHI
Application Number:
JP21450289A
Publication Date:
April 04, 1991
Filing Date:
August 21, 1989
Export Citation:
Assignee:
SANKYO CO
International Classes:
C12P21/02; A61K38/00; A61P35/00; C07K14/00; C07K14/52; C07K14/525; C12N15/19; C12R1/19; (IPC1-7): A61K37/02; C07K13/00; C12N15/19; C12P21/02
Attorney, Agent or Firm:
Akio Ohno
Next Patent: NOVEL ANTIGEN AND ITS PREPARATION