Title:
キトサンと酸性生体高分子とのハイブリッド繊維および動物細胞培養基材
Document Type and Number:
Japanese Patent JP3774466
Kind Code:
B2
Abstract:
It is intended to provide a three-dimensional scaffolds appropriate for culturing animal cells such as chondrocytes and fibroblasts. These three-dimensional scaffolds which comprise a chitosan/acidic biopolymers hybrid fibers composed of chitosan or its salts in the inside of the fiber and complexes of chitosan with biodegradable acidic biopolymers coating the fiber surface, are made of fibers capable of retaining their shapes after allowing to stand Dulbecco's modified Eagle's medium (DMEM) containing 10 % of FBS (fetal bovine serum)at room temperature for 2 weeks.
Inventors:
Majima Norihito
Rinsei Iwasaki
Funakoshi Tadanao
Akio Minami
Shinichiro Nishimura
Seiichi Tokura
Kazuo Harada
Sachiko Nonaka
Nobuhiko Maekawa
Rinsei Iwasaki
Funakoshi Tadanao
Akio Minami
Shinichiro Nishimura
Seiichi Tokura
Kazuo Harada
Sachiko Nonaka
Nobuhiko Maekawa
Application Number:
JP2004517284A
Publication Date:
May 17, 2006
Filing Date:
June 26, 2003
Export Citation:
Assignee:
Bioorganic Chemistry Laboratory Co., Ltd.
International Classes:
D01F9/00; A61L27/20; A61L27/38; A61L27/48; A61L27/58; C12M3/00; C12N5/00; C12N5/07; C12N5/074; C12N5/077; C12N11/10; D01F8/16; D06M11/00; D06M11/38; A61K35/12
Domestic Patent References:
| JP2002291461A | ||||
| JP2002128958A | ||||
| JP3015475A | ||||
| JP6277038A | ||||
| JP6073103A | ||||
| JP9173362A | ||||
| JP9500298A | ||||
| JP2002146086A | ||||
| JP2002078484A | ||||
| JP2001238663A |
Other References:
日本整形外科学会雑誌,2002 Aug,76(8),S1021
Attorney, Agent or Firm:
Kyousei Tamura
Toshio Ueda
Nagatoshi Shinagawa
Toshio Ueda
Nagatoshi Shinagawa