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Title:
HYDROPHILIC VEHICLE-BASED DUAL CONTROLLED RELEASE MATRIX SYSTEM
Document Type and Number:
Japanese Patent JP2013216680
Kind Code:
A
Abstract:

To provide a dual controlled release liquid matrix capable of minimizing or preventing misuse of an agent in a controlled release formulation (especially an agent such as an opioid analgesic having a tendency of being overused) for a low doze agent.

A dual controlled release matrix system, which is suitable for encapsulation in a hard capsule or a soft capsule, includes a hydrophilic vehicle (for example, a combination of high molecular weight polyethylene glycol and low molecular weight polyethylene glycol) for controlled release of one or more pharmaceutically active materials and a hydrogel forming polymer material dissolved or dispersed in the hydrophilic vehicle.


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Inventors:
SUKURU KARUNAKAR
Application Number:
JP2013133677A
Publication Date:
October 24, 2013
Filing Date:
June 26, 2013
Export Citation:
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Assignee:
BANNER PHARMACAPS INC
International Classes:
A61K9/66; A61K31/196; A61K31/4402; A61K31/554; A61K45/00; A61K47/10; A61K47/26; A61K47/32; A61K47/34; A61K47/36; A61K47/38
Domestic Patent References:
JPS6322032A1988-01-29
JP2004530669A2004-10-07
JP2005529104A2005-09-29
JP2003508434A2003-03-04
JP2003055254A2003-02-26
Foreign References:
US4708834A1987-11-24
US6027746A2000-02-22
Attorney, Agent or Firm:
Seiji Ohno
Reiko Tanaka
Yuko Matsuniya
Ken Kitano
Natsuki Ito



 
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