Title:
【発明の名称】アセチレンアリールスルホンアミドおよびホスフィン酸アミドヒドロキサム酸TACE阻害剤
Document Type and Number:
Japanese Patent JP2003524617
Kind Code:
A
Abstract:
Hydroxamic acids having formula (B) wherein the variables are as defined herein, are useful in treating disease conditions mediated by TNF- alpha such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
Inventors:
Levin, The Elemiy Iron
Chien, the ames ming
Chien, the ames ming
Application Number:
JP2000595967A
Publication Date:
August 19, 2003
Filing Date:
January 27, 2000
Export Citation:
Assignee:
American Cyanamid Company
International Classes:
A61K31/18; A61K31/351; A61K31/40; A61K31/4409; A61K31/495; A61P1/00; A61P1/02; A61P1/04; A61P1/16; A61P5/50; A61P7/02; A61P9/00; A61P9/04; A61P9/08; A61P9/10; A61P13/12; A61P17/02; A61P17/16; A61P19/00; A61P19/02; A61P19/08; A61P25/04; A61P25/28; A61P27/02; A61P27/10; A61P29/00; A61P31/18; A61P35/04; A61P37/06; A61P43/00; C07C303/40; C07C309/42; C07C309/87; C07C311/00; C07C311/29; C07D213/68; C07D295/12; C07D309/12; C07F9/36; C07D295/08; (IPC1-7): C07C311/29; A61K31/18; A61K31/351; A61K31/40; A61K31/4409; A61K31/495; A61P1/00; A61P1/02; A61P1/04; A61P1/16; A61P5/50; A61P7/02; A61P9/00; A61P9/04; A61P9/08; A61P9/10; A61P13/12; A61P17/02; A61P17/16; A61P19/00; A61P19/02; A61P19/08; A61P25/04; A61P25/28; A61P27/02; A61P27/10; A61P29/00; A61P31/18; A61P35/04; A61P37/06; A61P43/00; C07C303/40; C07C309/42; C07C309/87; C07D213/68; C07D295/08; C07D295/12; C07D309/12
Attorney, Agent or Firm:
Heiyoshi Odashima