Title:
【発明の名称】X-関連アポトーシス阻害剤発現のアンチセンスモジュレーション
Document Type and Number:
Japanese Patent JP2003508090
Kind Code:
A
Abstract:
Antisense compounds, compositions and methods are provided for modulating the expression of X-linked inhibitor of apoptosis. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding X-linked inhibitor of apoptosis. Methods of using these compounds for modulation of X-linked inhibitor of apoptosis expression and for treatment of diseases associated with expression of X-linked inhibitor of apoptosis are provided.
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Inventors:
Bennett, Sea Frank
Ackerman, Elizabeth Jay
Kausart, Rex M
Ackerman, Elizabeth Jay
Kausart, Rex M
Application Number:
JP2001522247A
Publication Date:
March 04, 2003
Filing Date:
January 11, 2000
Export Citation:
Assignee:
Isis PharmaceuticalsInc
International Classes:
A61K31/7115; A61K31/712; A61K31/7125; A61K48/00; A61P15/00; A61P29/00; A61P35/00; C12N15/113; C12N15/09; C12N15/15; A61K38/00; (IPC1-7): C12N15/09; A61K31/7115; A61K31/712; A61K31/7125; A61K48/00; A61P15/00; A61P29/00; A61P35/00
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)