Title:
【発明の名称】遺伝子破壊用条件付遺伝子トラッピング構築物
Document Type and Number:
Japanese Patent JP2003512053
Kind Code:
A
Abstract:
The present invention relates to a gene trapping construct which causes conditional mutations in genes, and the use of this gene trapping construct to mutationally inactivate all cellular genes. In addition the invention relates to a cell, preferably a mammalian cell which contains the above mentioned construct. Moreover, the invention relates to the use of said cell for identification and/or isolation of genes and for the creation of transgenic organisms to study gene function at various developmental stages, including the adult. In conclusion, the present invention provides a process which enables a temporally and/or spatially restricted inactivation of all genes that constitute a living organism.
Inventors:
Ralph Kuhn
Harald von Melchener
Joachim Altshmeet
Harald von Melchener
Joachim Altshmeet
Application Number:
JP2001532191A
Publication Date:
April 02, 2003
Filing Date:
October 16, 2000
Export Citation:
Assignee:
ARTEMIS PHARMACEUTICALS GMBH
Frankgen Biotech Hinologie Akchengezel Shaft
Frankgen Biotech Hinologie Akchengezel Shaft
International Classes:
A01K67/027; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/10; C12N15/90; C12Q1/02; (IPC1-7): C12N15/09; A01K67/027; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12Q1/02
Foreign References:
| WO1999050426A1 | 1999-10-07 |
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)