Title:
【発明の名称】蛋白質分子立体構造解析装置
Document Type and Number:
Japanese Patent JP3073092
Kind Code:
B2
Abstract:
PURPOSE:To provide a device which backs up to objectively evaluate how the interactions recognized among the local structures of protein molecules contribute to the construction of the cubic structure of the protein molecule in regard of a protein molecule cubic structure analyzer which calculates the dependence/mutual dependence degrees to show the way of interactions approved among the local cubic structures of the protein molecules. CONSTITUTION:An amino acid inter-residue interaction calculation part 14 calculates the degree of interaction between the amino acid residues based on the coordinate data inputted through a coordinate data input processing part 12 and the definition information on the local structure of a protein molecule inputted through a local structure definition input processing part 13. Based on the calculation result of the part 14, an inter-local structure interaction calculation part 15 calculates the degree of interaction between the local structures. Based on the result of this calculation, a dependence degree calculation part 16 or a mutual dependence degree calculation part 20 calculates the dependence degree of each local structure onto another local structure or the mutual dependence degree between the local structures and outputs this calculation result.
Inventors:
Hiroshi Matsuo
Application Number:
JP7490192A
Publication Date:
August 07, 2000
Filing Date:
March 31, 1992
Export Citation:
Assignee:
富士通株式会社
International Classes:
G01N33/68; C07K14/00; G01N35/00; G06F17/00; G06F17/30; G06F17/50; G06F19/00; G06F19/16; G06Q50/00; G06Q50/10; G06Q50/22; (IPC1-7): G06F17/00; G01N35/00; G06F17/30
Other References:
Ｂ．Ｂｕｓｅｔｔａ＆Ｙ．Ｂａｒｒａｎｓ”Ｔｈｅ Ｐｒｅｄｉｃｔｉｏｎ ｏｆ Ｐｒｏｔｅｉｎ Ｔｏｐｏｌｏｇｉｅｓ”，Ｂｉｏｃｈｉｍｉｃａ ｅｔ Ｂｉｏｐｈｙｓｉｃａ Ａｃｔａ，Ｖｏｌ．７０９，Ｎｏ．１，ｐ．７３−８３，１９８２（昭５７−１２−６）
Ｗ．Ｒ．Ｔａｙｌｏｒ”Ｔｏｗａｒｄｓ ｐｒｏｔｅｉｎ ｔｅｒｔｉａｒｙ ｆｏｌｄ ｐｒｅｄｉｃｔｉｏｎ ｕｓｉｎｇ ｄｉｓｔａｎｃｅ ａｎｄ ｍｏｔｉｆ ｃｏｎｓｔｒａｉｎｔｓ”，ＰＲＯＴＥＩＮ ＥＮＧＩＮＥＥＲＩＮＧ，Ｖｏｌ．４，Ｎｏ．８，１９９１，ｐ．８５３−８７０
斎藤「蛋白質の立体構造の予測」生物物理，Ｖｏｌ．２５，Ｎｏ．６，ｐ．２４５−２５４，１９８５（昭６０−１１−２５）
Ｗ．Ｒ．Ｔａｙｌｏｒ”Ｔｏｗａｒｄｓ ｐｒｏｔｅｉｎ ｔｅｒｔｉａｒｙ ｆｏｌｄ ｐｒｅｄｉｃｔｉｏｎ ｕｓｉｎｇ ｄｉｓｔａｎｃｅ ａｎｄ ｍｏｔｉｆ ｃｏｎｓｔｒａｉｎｔｓ”，ＰＲＯＴＥＩＮ ＥＮＧＩＮＥＥＲＩＮＧ，Ｖｏｌ．４，Ｎｏ．８，１９９１，ｐ．８５３−８７０
斎藤「蛋白質の立体構造の予測」生物物理，Ｖｏｌ．２５，Ｎｏ．６，ｐ．２４５−２５４，１９８５（昭６０−１１−２５）
Attorney, Agent or Firm:
Yoshiyoshi Ogasawara (2 outside)