Title:
【発明の名称】酸感受性アミドの立体選択的製造及び該製造に有用な中間体
Document Type and Number:
Japanese Patent JPH06501466
Kind Code:
A
Abstract:
This invention is directed to certain dibenzofurancarboxamides and dibenzofurancarboxamide acids and their use as 5HT3 antagonists having unique CNS, anti-emetic and gastric prokinetic activity void of any significant D2 receptor binding properties. Further, this invention relates to a process for the synthesis of stereoisomeric compounds having such CNS, anti-emetic and gastric prokinetic activity.
Inventors:
Powers Matthew Earl
Usey Raymond Dee
Stud William Elle
Gorec Fredrick A
Usey Raymond Dee
Stud William Elle
Gorec Fredrick A
Application Number:
JP51591191A
Publication Date:
February 17, 1994
Filing Date:
September 12, 1991
Export Citation:
Assignee:
Rhone-Poulin Roller International (Holdings) Incorporated
International Classes:
C07D405/04; C07C231/08; C07C231/18; C07C233/58; C07D405/12; C07D451/14; C07D453/02; C07D471/08; C07D491/052; C07D491/056; C07D493/04; C07D495/04; C07D497/04; C07D498/08; (IPC1-7): C07C233/58; C07C231/08; C07D405/04; C07D453/02; C07D471/08; C07D491/052; C07D491/056; C07D493/04; C07D495/04; C07D497/04
Attorney, Agent or Firm:
Minoru Nakamura (6 outside)