Title:
【発明の名称】PEMムチン縦列繰り返し配列特異性単クローン抗体の最小識別単位
Document Type and Number:
Japanese Patent JP3280966
Kind Code:
B2
Abstract:
PCT No. PCT/GB92/00746 Sec. 371 Date Sep. 29, 1993 Sec. 102(e) Date Sep. 29, 1993 PCT Filed Apr. 23, 1992 PCT Pub. No. WO92/18534 PCT Pub. Date Oct. 29, 1992The peptide EPPT (Glu-Pro-Pro-Thr)(SEQ I YD NO:1) selectively binds a mucin expressed by epithelial tumors. It may be incorporated into larger molecules, such as peptides consisting of the sequence EPPT and further amino acids to form a peptide of up to 30 amino acids, and may be radiolabelled or used to guide toxins, etc. to cells expressing the mucin.
Inventors:
Courtney-Luck, Nigel Stefan
Application Number:
JP50806192A
Publication Date:
May 13, 2002
Filing Date:
April 23, 1992
Export Citation:
Assignee:
Cancer Therapeutics Limited
International Classes:
A61P35/00; C07K1/00; C07K1/22; C07K5/113; C07K7/00; C07K7/06; C07K7/08; C07K14/00; C07K14/47; C07K16/00; A61K39/395; C07K16/18; C07K16/30; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/08; C12Q1/02; G01N33/53; G01N33/574; A61K38/00; (IPC1-7): C07K5/113; C07K7/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/08; C12Q1/02; G01N33/574
Other References:
Ｉｎｔ．Ｊ．Ｃａｎｃｅｒ，Ｖｏｌ．４４（１９８９），ｐ．６９１−６９６
Ｍｅｔｈｏｄｓ ｉｎ Ｅｎｚｙｍｏｌｏｇｙ，Ｖｏｌ．１７８（１９８９），ｐ．６７６−６９２
Ｍｏｌｅｃｕｌａｒ Ｉｍｍｕｎｏｌｏｇｙ，Ｖｏｌ．２７，Ｎｏ．８（１９９０），ｐ．７９５−８０２
Ｍｅｔｈｏｄｓ ｉｎ Ｅｎｚｙｍｏｌｏｇｙ，Ｖｏｌ．１７８（１９８９），ｐ．６７６−６９２
Ｍｏｌｅｃｕｌａｒ Ｉｍｍｕｎｏｌｏｇｙ，Ｖｏｌ．２７，Ｎｏ．８（１９９０），ｐ．７９５−８０２
Attorney, Agent or Firm:
Masatake Shiga (2 outside)