Title:
【発明の名称】コンタクトレンズを消毒するためにビス(ビグアニド)が増強された抗菌効力を提供する組成物および方法
Document Type and Number:
Japanese Patent JP2001504246
Kind Code:
A
Abstract:
The present invention is directed to an ophthalmically safe disinfecting solution for contact lenses comprising a bis(biguanide) having formula (I) wherein R<1> and R<4> are independently selected from the group consisting of branched or unbranched alkyl having 4-12 carbon atoms, ether or thioether radical having 4-12 carbon atoms, or cycloalkyl or cycloalkyl-alkyl radical having 5-12 carbon atoms; R<2> and R<3> are independently selected from the group consisting of hydrogen, alkyl having 1-12 carbon atoms, alkoxyalkyl having 1-12 carbon atoms, or cycloalkyl or cycloalkyl-alkyl having 5-12 carbon atoms; R<6> and R<7> are independently selected from the group consisting of hydrogen and alkyl radical having 1-6 carbon atoms, and A in the above formula is selected from the divalent radical having 4-16 carbon atoms consisting of a divalent alkyl, alkyloxyalkyl, alkylsulfide, or a polymethylene interrupted with a cyclic divalent radical. In one embodiment of the present invention, such biguanides may be combined with a polymeric biguanide for complementary or synergistic biocidal efficacy. The invention is also directed to an improved method of disinfecting a contact lens.
Inventors:
Spooner, Susan Pee.
Halar, David Jay.
Simpson, Lisa Sea.
Marsh, David A.
Halar, David Jay.
Simpson, Lisa Sea.
Marsh, David A.
Application Number:
JP52263298A
Publication Date:
March 27, 2001
Filing Date:
November 04, 1997
Export Citation:
Assignee:
Bosch & Rom Incorporated
International Classes:
G02C13/00; A01N47/44; A61L2/18; A61L12/14; (IPC1-7): G02C13/00; A01N47/44; A61L2/18
Attorney, Agent or Firm:
Shusaku Yamamoto