Title:
【発明の名称】一酸化窒素供与体及び還元剤を含有するマトリックス並びにその使用
Document Type and Number:
Japanese Patent JP2003527209
Kind Code:
A
Abstract:
A composition comprises a hydrophobic matrix, a reducible nitric oxide (NO) donor, and an intrinsic reductant reactably associated together with the reducible NO donor within the matrix, and releases an effective amount of NO from the matrix when wetted at physiological pH, independently of the presence or absence of extrinsic reducing agents. The composition inhibits the growth of target cells in a target medium.
More Like This:
Inventors:
E You Tsao
James A Bratz
Gerald M. Rosen
James A Bratz
Gerald M. Rosen
Application Number:
JP2001568397A
Publication Date:
September 16, 2003
Filing Date:
March 20, 2001
Export Citation:
Assignee:
Novovascular Incorporated
International Classes:
A61K31/198; A61K31/295; A61K31/375; A61K33/00; A61K33/26; A61K33/42; A61K35/14; A61K47/34; A61L27/00; A61L27/34; A61L27/54; A61L29/08; A61L29/16; A61L31/10; A61L31/16; A61L33/00; A61P1/00; A61P7/02; A61K9/00; A61P9/00; A61P9/08; A61P15/00; A61P15/10; A61P31/00; A61P31/04; A61P31/10; A61P31/12; A61P35/00; A61P37/04; A61P43/00; A61K9/20; (IPC1-7): A61L27/00; A61K9/00; A61K33/00; A61K35/14; A61K47/34; A61L33/00; A61P1/00; A61P7/02; A61P9/00; A61P9/08; A61P15/00; A61P15/10; A61P31/00; A61P31/04; A61P31/10; A61P31/12; A61P35/00; A61P37/04; A61P43/00
Foreign References:
| WO1999000070A1 | 1999-01-07 | |||
| WO1999067210A1 | 1999-12-29 | |||
| WO1999008482A1 | 1999-02-18 | |||
| WO1998005689A1 | 1998-02-12 | |||
| WO1998043621A1 | 1998-10-08 |
Attorney, Agent or Firm:
Masaki Hirota (4 others)