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Patent Searching and Data


Title:
【発明の名称】無症候性患者における糖尿病可能性評価方法
Document Type and Number:
Japanese Patent JP3425149
Kind Code:
B2
Abstract:
Assays for identifying human patients at risk for developing insulin-dependent diabetes mellitus rely on detection of autoantibodies to a 38 kD autoantigen present in pancreatic beta-cells in patient sera. It has been found that autoantibodies to this particular autoantigen developed in patients well before clinical onset of the disease in a significant subpopulation of prediabetic patients. Useful assays will frequently combine detection of autoantibodies to the 38 kD autoantigen with detection of other known markers of IDDM, such as autoantibodies to a 64 kD autoantigen (glutamic acid decarboxylase).

Inventors:
Beckeskov, Steinan
Aenstooth, Genk-Jean
Application Number:
JP52334094A
Publication Date:
July 07, 2003
Filing Date:
April 08, 1994
Export Citation:
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Assignee:
The Regents of the University of California
International Classes:
A61K39/00; A61K39/395; G01N33/564; (IPC1-7): G01N33/564; A61K39/00; A61K39/395
Other References:
NATURE,VOL.298,167−169
NATURE,VOL.347,151−156
Attorney, Agent or Firm:
Atsushi Nakajima (3 outside)