Title:
【発明の名称】血流減少に由来する組織障害の処置及び予防のためのAICAリボシド化合物の用途
Document Type and Number:
Japanese Patent JPH06503359
Kind Code:
A
Abstract:
Methods of preventing tissue damage associated with decreased blood flow in a human by administering AICA riboside or a prodrug thereof in an amount which provides a blood plasma concentration of between 1 <0>g/ml and 20 <0>g/ml of AICA riboside for a time sufficient to reduce the risk of said tissue damage in said human. Methods of preventing an adverse clinical outcome, such as an adverse cardiovascular arid/or cerebrovascular event, in a patient at risk for such outcome by administering AICA riboside or a prodrug thereof in an amount which provides a blood plasma concentration of between 1 <0>g/ml and 20 <0>g/ml of AICA riboside for a time sufficient to reduce the risk for said patient.
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Inventors:
Glover, Harry Edward
Marlene, Kevin Michael
Raykind, Paul Kevin
Marlene, Kevin Michael
Raykind, Paul Kevin
Application Number:
JP50644893A
Publication Date:
April 14, 1994
Filing Date:
September 28, 1992
Export Citation:
Assignee:
GENSIA PHARMACEUTICALS, INCORPORATED
International Classes:
A61K31/00; A61K31/70; A61K31/13; A61K31/7042; A61K31/7052; A61K31/7056; A61P9/00; C07H19/052; A61K; (IPC1-7): A61K31/70
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)