Title:
イミノピロリドンチオールアミノ酸複合体、薬学的組成物および癌の治療方法
Document Type and Number:
Japanese Patent JP2010522759
Kind Code:
A
Abstract:
Compounds, compositions and methods for the treatment of cancer are disclosed herein. Embodiments of the present invention include compounds having the formula: (I), wherein R1 is selected from hydrogen or substituted or unsubstituted (C1-C6) alkyl or (C3-C6) cycloalkyl, R2 and R3 are independently selected from hydrogen, substituted or unsubstituted (C1-C6) alkyl, (C4-C6) cycloalkyl, or taken together with the N atom to which they are attached form a 3-6 membered heterocycloalkyl, and n is 1-5. Embodiments of the present invention also include pharmaceutical compositions comprising compounds of Formula (I) or pharmaceutically acceptable salts thereof, and methods of treating cancer via the administration of such compounds to patients in need of such treatment.
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Inventors:
Mayers, Ross Oh.
Dore, Robert Tee.
Dore, Robert Tee.
Application Number:
JP2010501060A
Publication Date:
July 08, 2010
Filing Date:
March 14, 2008
Export Citation:
Assignee:
The Arizona Board of Regents on Behalf of the University of Arizona
International Classes:
C07D233/88; A61K31/4166; A61P35/00; A61P35/02
Attorney, Agent or Firm:
Takehiko Suzue
Kurata Masatoshi
Satoshi Kono
Makoto Nakamura
Yoshihiro Fukuhara
Takashi Mine
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Katsu Sunagawa
Kurata Masatoshi
Satoshi Kono
Makoto Nakamura
Yoshihiro Fukuhara
Takashi Mine
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Katsu Sunagawa