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Title:
グラム陰性細菌性、例えば髄膜炎菌性の感染または疾患に対する免疫原性組成物またはワクチン
Document Type and Number:
Japanese Patent JP2013522177
Kind Code:
A
Abstract:
The present invention relates to the field of Gram-negative bacterial immunogenic compositions and vaccines, their manufacture and the use of such compositions in medicine. More particularly, it relates to immunogenic compositions comprising outer membrane proteins of Gram-negative bacteria which are involved in uptake of extracellular zinc.

Inventors:
Devos, Natalie, Isabel
Poolman, Jean
Stork, michelle
Tomasen, Johannes, Petrus, Maria
Vinants, Vincent
Application Number:
JP2012556531A
Publication Date:
June 13, 2013
Filing Date:
March 11, 2011
Export Citation:
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Assignee:
GlaxoSmithKline Biologicals Society Anonymous
Utrecht University
International Classes:
A61K39/02; A61K39/00; A61K39/095; A61K39/10; A61K39/102; A61K39/104; A61K39/395; A61K47/48; A61P29/00; A61P31/04; C07K16/00; C12P21/02; C12N15/09
Domestic Patent References:
JP2003532404A2003-11-05
JP2004500801A2004-01-15
JP2003514868A2003-04-22
JP2003500420A2003-01-07
JP2006506467A2006-02-23
JP5584683B22014-09-03
Foreign References:
WO2010025964A12010-03-11
Other References:
STORK, M. ET AL., 16TH INTERNATIONAL PATHOGENIC NEISSERIA CONFERENCEABSTRACTS ORAL PRESENTATIONS, 20, JPN6015008402
MICROBIOLOGY, 2001, 147(5), P.1277-90, JPN6016006672
DATABASE UNIPROTKB [ONLINE], ACCESSION NO.Q9JZN9, THE SEQUENCE WAS LAST MODIFIED OCT. 1, 2001., JPN6016037262
HUMAN VACCINES, 2005, VOL.1, NO.2, PP.80-84, JPN6016037263
PROTEOMICS, 2006, VOL.6, PP.3400-3413, JPN6016037264
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka