Title:
インターフェロンアルファを誘導する免疫刺激オリゴヌクレオチド
Document Type and Number:
Japanese Patent JP3976742
Kind Code:
B2
Abstract:
An immunostimulatory oligonucleotide that is represented by the general formula 5′-Gm-GACGATCGTC-Gn-3′ or 5′-Gm-CACGATCGTG-Gn-3′ (in the formula, m and n are each independently an integer from 1 to 9 and m+n=10) and that comprises any of the following base sequences: GGACGATCGTCGGGGGGGGG (SEQ. ID. NO.: 1), GGGACGATCGTCGGGGGGGG (SEQ. ID. NO.: 2), GGGGACGATCGTCGGGGGGG (SEQ. ID. NO.: 3), GGGGGGGACGATCGTCGGGG (SEQ ID NO: 4), GGGGGGGGACGATCGTCGGG (SEQ. ID. NO.: 5), GGGGGGGGGACGATCGTCGG (SEQ. ID. NO.: 6), GGGGGGGGGGACGATCGTCG (SEQ. ID. NO.: 7), and GGGGGGGGGCACGATCGTGG (SEQ. ID. NO.: 8).
Inventors:
Kitagawa Haruka
Sumiko Ibo
Takasumi Matsuki
Saburo Yamamoto
Sumiko Ibo
Takasumi Matsuki
Saburo Yamamoto
Application Number:
JP2004053795A
Publication Date:
September 19, 2007
Filing Date:
February 27, 2004
Export Citation:
Assignee:
Emori Trading Co., Ltd.
National University Corporation Fukui University
Director, National Institute of Infectious Diseases
Fukui Industry Support Center
National University Corporation Fukui University
Director, National Institute of Infectious Diseases
Fukui Industry Support Center
International Classes:
C12N15/09; A61K31/7088; A61K39/00; A61K39/39; A61K45/00; A61K45/06; A61K48/00; A61P1/16; A61P11/02; A61P11/06; A61P17/00; A61P17/02; A61P17/04; A61P31/04; A61P31/06; A61P31/10; A61P31/12; A61P35/00; A61P37/04; A61P37/08; A61P43/00
Foreign References:
| WO2004000351A1 | ||||
| WO2003024481A1 | ||||
| WO2003024480A1 | ||||
| WO2004100965A1 | ||||
| WO2004084939A1 | ||||
| WO2004085635A1 | ||||
| WO2004084940A1 |
Other References:
Jpn J Cancer Res 83(11) p.1128-1131 (1992)
J Immunol 163(7) p.3642-3652 (1999)
J Immunol 163(7) p.3642-3652 (1999)
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Masaya Nishiyama
Takashi Ishida
Fukumoto product
Tetsuji Koga
Masaya Nishiyama