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Title:
IMPROVER FOR LIVER DISORDER
Document Type and Number:
Japanese Patent JPS60258115
Kind Code:
A
Abstract:

PURPOSE: An improver for liver disorder having an inhibitory action on GPT in serum and yet high safety, containing chamigrenal, chamigrenol, etc. extracted from dried fruit of Schizandra chinensis Baillon of the family Schizandraceae of Chinese and Japanese drug as an active ingredient.

CONSTITUTION: An improver containing a compound shown by the formula (R is aldehyde, hydroxymethyl, carboxyl, or carbomethoxy) as an active ingredient. The compound shown by the formula, namely, chamigrenal (R is aldehyde), chamigrenol (R is hydroxymethyl), chamigrenic acid (R is COOH), etc. is found to have improving action on liver disorder like lignan in purified oil of Schizandra chinensis Baillon of the family Schizandraceae. The compound shown by the formula suppresses rise in GPT value caused by CCl4 in serum, but has extremely high safety.


Inventors:
HIKINO HIROSHI
HOSAKA KUNIO
OGAWA YOSHIMITSU
IKETANI YUKINOBU
KUBOTA KIYOSHI
TAGUCHI HEIHACHIROU
Application Number:
JP11312184A
Publication Date:
December 20, 1985
Filing Date:
June 04, 1984
Export Citation:
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Assignee:
HIKINO HIROSHI
TSUMURA JUNTENDO KK
International Classes:
C07C47/45; A61K31/045; A61K31/11; A61K31/19; A61K31/215; A61P1/16; C07C27/00; C07C33/14; C07C45/00; C07C47/445; C07C51/00; C07C61/35; C07C67/00; C07C69/753; (IPC1-7): A61K31/045; A61K31/11; A61K31/19; A61K31/215; C07C33/14; C07C47/445; C07C61/35; C07C69/753
Attorney, Agent or Firm:
Yusuke Hiraki