細胞壊死阻害剤としてのインドール化合物

Japanese Patent JP5323834

B2

The present invention relates to indole or indazole compounds, pharmaceutically acceptable salts or isomers thereof which are useful for the prevention or treatment of cellular necrosis and necrosis-associated diseases. The present invention also relates to a method and a composition for the prevention or treatment of cellular necrosis and necrosis-associated diseases, comprising said indole or indazole compounds as an active ingredient.

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Kim Seung Ha
Kim Hyung Jin
Koo Sung Young
Lee Sumbe
Park Hisul
Yoon Seung Hyun
Baek Seung-yeob
Kwak Hyo Shin
Seo Dong Wook
Park Ok

JP2010521774A

October 23, 2013

August 18, 2008

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LG Life Sciences Ltd.

C07D413/04; A61K31/422; A61K31/4245; A61K31/427; A61K31/4439; A61K31/454; A61K31/496; A61K31/497; A61K31/4985; A61K31/506; A61K31/5377; A61K31/541; A61K45/00; A61P1/04; A61P1/14; A61P1/16; A61P1/18; A61P3/00; A61P3/10; A61P5/38; A61P9/10; A61P9/14; A61P11/00; A61P11/16; A61P13/00; A61P13/12; A61P15/00; A61P17/02; A61P17/06; A61P19/02; A61P21/00; A61P21/04; A61P25/00; A61P25/14; A61P25/16; A61P25/30; A61P25/32; A61P29/00; A61P31/04; A61P31/06; A61P31/12; A61P35/02; A61P39/02; A61P43/00; C07D413/14; C07D417/04; C07D417/14; C07D487/04; C07F9/6539

JP7165708A

WO2004018428A1
WO2008050821A1
WO2009082152A1
WO2006024535A1
WO2009088192A1
WO2006112549A1

B. Narayana et al.,Bioorganic & Medicinal Chemistry,2005年,Vol.13,p.4638-4644
Ji-Yeon Lee et al.,Supramoecular Chemistry,2007年,Vol.19(4-5),p.257-263

Kyousei Tamura
Samejima Mutsumi
Masahiro Nitta

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