Title:
リジン特異的デメチラーゼ-1の阻害剤
Document Type and Number:
Japanese Patent JP6430512
Kind Code:
B2
Abstract:
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of lysine specific demethylase-1. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
Inventors:
Chen, Young, Kay.
Kanouni, Tofique
Kardeau, Stefin, W.
Stafford, Jeffrey, Alan
Vir, james, marvin
Kanouni, Tofique
Kardeau, Stefin, W.
Stafford, Jeffrey, Alan
Vir, james, marvin
Application Number:
JP2016538535A
Publication Date:
November 28, 2018
Filing Date:
December 10, 2014
Export Citation:
Assignee:
Celgene Quantisell Research, Inc.
International Classes:
C07D239/42; A61K31/4155; A61K31/4375; A61K31/454; A61K31/4965; A61K31/505; A61K31/517; A61K31/5375; A61K31/5386; A61K31/551; A61P35/00; A61P43/00; C07D401/04; C07D401/06; C07D401/12; C07D401/14; C07D405/12; C07D405/14; C07D413/12; C07D417/06; C07D471/04; C07D471/10; C07D471/18; C07D487/04; C07D487/10; C07D498/18; C07D519/00
Domestic Patent References:
JP2006514118A | ||||
JP2011529468A | ||||
JP2010520892A | ||||
JP2009525337A | ||||
JP2005500294A |
Foreign References:
WO2013175789A1 | ||||
WO2010046780A2 | ||||
WO2012013727A1 |
Attorney, Agent or Firm:
Kazuhiro Kiyohara
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