Title:
ＡＰＯＬ１の阻害剤及びこれを使用する方法
Document Type and Number:
Japanese Patent JP2023530271
Kind Code:
A
Abstract:
本開示は、式（Ｉ）の化合物、その重水素化誘導体、及び前述のうちのいずれかの薬学的に許容される塩から選択される少なくとも１つの化合物、重水素化誘導体、又は薬学的に許容される塩、同化合物を含む組成物、並びにＡＰＯＬ１媒介性腎臓疾患の治療における使用を含む、同化合物を作製及び使用する方法を提供する。TIFF2023530271000273.tif6792
Inventors:
Tsao, Jinlong
Cam, John H.
Dakin, Leslie A.
Dennis, Francois
Dorsch, Warren A.
Fotia, Ann
Hamel, Martin
Kluger, Elaine Bee.
Redford, Brian
Maltheis, François
Nantha Kumar, Sgantinies.
Nicholas, Olivier
Sayeg, Camille Yee.
Center, Timothy Jay.
Wang, Tian Shen
Cam, John H.
Dakin, Leslie A.
Dennis, Francois
Dorsch, Warren A.
Fotia, Ann
Hamel, Martin
Kluger, Elaine Bee.
Redford, Brian
Maltheis, François
Nantha Kumar, Sgantinies.
Nicholas, Olivier
Sayeg, Camille Yee.
Center, Timothy Jay.
Wang, Tian Shen
Application Number:
JP2022575989A
Publication Date:
July 14, 2023
Filing Date:
June 11, 2021
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
C07D209/42; A61K31/403; A61K31/4155; A61K31/4178; A61K31/4184; A61K31/4192; A61K31/4196; A61K31/4245; A61K31/433; A61K31/437; A61K31/454; A61K31/4704; A61K31/501; A61K31/506; A61K31/5377; A61P13/12; C07D401/12; C07D403/08; C07D403/12; C07D405/08; C07D405/12; C07D405/14; C07D409/12; C07D413/12; C07D417/12; C07D471/04
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto