Title:
インスリン−オリゴマー複合体、その処方物及び使用
Document Type and Number:
Japanese Patent JP5721266
Kind Code:
B2
Abstract:
The invention provides a complex including a cation and an insulin compound conjugate. The insulin compound conjugate includes insulin compound, such as human insulin or an analog thereof, conjugated to a modifying moiety, such as a polyethylene glycol moiety. The invention also includes solids and pharmaceutical compositions including such complexes, methods of making such complexes, and methods of using such complexes in the treatment of insulin compound deficiencies and other ailments. Further, the invention includes novel insulin compound conjugates and modifying moieties for use in making novel insulin compound conjugates. The invention also includes fatty acid compositions for administration of pharmaceutical agents, such as the novel insulin compound conjugates, and/or the cation-insulin compound conjugate complexes of the invention.
Inventors:
Rado Crisnan, Balasiam
Aggerwold, Diti
Ferro, michel
Kenice, James Dee.
Marker, Nab Deep, Bee.
Mirror, Mark, A.
Public, Leo
Polowi, Karan
Pushkin, Karan
Ekwillibe, Notcholi, N.
Aggerwold, Diti
Ferro, michel
Kenice, James Dee.
Marker, Nab Deep, Bee.
Mirror, Mark, A.
Public, Leo
Polowi, Karan
Pushkin, Karan
Ekwillibe, Notcholi, N.
Application Number:
JP2011151149A
Publication Date:
May 20, 2015
Filing Date:
July 07, 2011
Export Citation:
Assignee:
BIOCON LIMITED
International Classes:
C07K14/62; A61K38/00; A61K38/28; A61P3/10
Domestic Patent References:
| JP2003113113A | ||||
| JP2004501188A | ||||
| JP2002512265A | ||||
| JP8053452A | ||||
| JP8041061A |
Foreign References:
| WO2002064627A2 | ||||
| WO2004039838A1 | ||||
| WO2002036169A2 | ||||
| WO2003045330A2 |
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito