Title:
アゾール誘導体製造方法における中間体ハロフェニル誘導体およびそれらの使用
Document Type and Number:
Japanese Patent JP4125672
Kind Code:
B2
Abstract:
Novel halophenyl derivatives of the general formula (I), wherein R1 is halogen, a leaving group or 1H-1,2,4-triazol-1-yl and R2 is ethynyl or carboxy, X1 is halogen and X2 and X3 are each independently hydrogen or halogen, and their manufacture are described. They are intermediates for manufacturing azole derivatives of the general formula (V) which are valuable medicaments useful for treating systemic mycoses.
Inventors:
Soukup, Milan
Application Number:
JP2003508683A
Publication Date:
July 30, 2008
Filing Date:
June 17, 2002
Export Citation:
Assignee:
Basilea Pharmaceutica AG
International Classes:
C07C29/42; C07B61/00; C07C29/34; C07C33/48; C07C51/285; C07C51/29; C07C57/58; C07C59/115; C07D249/08; C07D417/06; C07D521/00
Domestic Patent References:
| JP5213906A |
Foreign References:
| WO1997031903A1 |
Other References:
Journal of Organic Chemistry,1995年,Vol.60, No.10,p.3000-3012
Chemical & Pharmaceutical Bulletin,1992年,Vol.40, No.3,p.661-665
Chemical & Pharmaceutical Bulletin,1998年,Vol.46, No.4,p.623-630
Chemical & Pharmaceutical Bulletin,1992年,Vol.40, No.3,p.661-665
Chemical & Pharmaceutical Bulletin,1998年,Vol.46, No.4,p.623-630
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda