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Title:
INTRAORAL DISINTEGRATION-TYPE TABLET CONTAINING VITAMIN K
Document Type and Number:
Japanese Patent JP2000344664
Kind Code:
A
Abstract:

To provide an intraoral disintegration-type tablet containing vitamin K and to provide a method for producing the same tablet.

This tablet is prepared by tabletting wet powder comprising vitamin K adsorbed by crystalline cellulose, at least one of saccharides and a solvent. The tablet is produced by adsorbing vitamin K with crystalline cellulose, by granulating them using a mixture of water with an alcohol and then by mixing the resultant particles with at least one of saccharides, followed by humidifying them with water and/or an alcohol and tabletting them. The resultant tablet disintegrates within 30 s in the mouth.


Inventors:
IKEMATSU YASUYUKI
HASHIZUME MINORU
NAKAMURA MASAHIRO
ANDO EISHIN
Application Number:
JP15183599A
Publication Date:
December 12, 2000
Filing Date:
May 31, 1999
Export Citation:
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Assignee:
EISAI CO LTD
International Classes:
A61K9/20; A61K31/00; A61K31/12; A61K31/122; A61K47/26; A61K47/38; A61P3/00; A61P3/02; (IPC1-7): A61K31/122; A61K9/20; A61K47/26; A61K47/38; A61P3/02