Title:
ヨウ素化X線コントラスト媒体
Document Type and Number:
Japanese Patent JP3606583
Kind Code:
B2
Abstract:
The invention provides iodinated bis phenyl compounds, useful as X-ray contrast agents, of formula I (wherein each C6R5 moeity may be the same or different; each R denotes a hydrogen or iodine atom or a group M, two or three non-adjacent R groups on each C6R5 moiety denoting iodine atoms and one, two or three R groups on each C6R5 moiety denoting M groups; X denotes a group providing a 1, 2 or 3 atom chain linking the two C6R5 groups, preferably where X is or contains in the bridging chain a carbonyloxy group each C6R5 group being a triodophenyl group or a group in which each R is other than hydrogen; and each M is independently a non-ionic hydrophilic moiety, M preferably being a non-ionic hydrophilic moiety comprising a monohydroxy- or polyhydroxy-alkyl group) and isomers, especially stereoisomers and rotamers, thereof.
Inventors:
Anna Lydbeck
Almen, Torsten
Sunning, michel
Anderson, Sven
Wystrand, Lars-Golan
Gorman, Claes
Almen, Torsten
Sunning, michel
Anderson, Sven
Wystrand, Lars-Golan
Gorman, Claes
Application Number:
JP51070596A
Publication Date:
January 05, 2005
Filing Date:
September 22, 1995
Export Citation:
Assignee:
Amersham Health Aksuye Sersukapu
International Classes:
A61K49/04; C07C33/46; C07C43/295; C07C49/255; C07C49/83; C07C69/02; C07C69/12; C07C233/25; C07C235/16; C07C237/46; C07C275/28; C07C275/40; C07C275/42; C07C307/10; C07C311/29; C07C317/22; (IPC1-7): C07C237/46; A61K49/04; C07C275/40
Domestic Patent References:
| JP10505857A |
Foreign References:
| US5348727 | ||||
| WO1994014478A1 | ||||
| WO1993016375A1 | ||||
| WO1993010078A1 | ||||
| WO1993012071A1 | ||||
| WO1993010825A1 |
Attorney, Agent or Firm:
Shunichiro Suzuki