Title:
LINKING AGENT AND ITS USE METHOD
Document Type and Number:
Japanese Patent JPH021464
Kind Code:
A
Abstract:
NEW MATERIAL: Analogs comprising compd. of formula I [wherein R1 is NH2- or NH2-NH-; R2 is -NH-C(O)-, -C(O)-, etc.; R3 is a 1-10C alkylene, a phenyl- substd. 1-10C alkylene, an arylene, etc.; R4 is H, an acetyl, formula, II, formula III, etc.; m and n are each 0 or 1], their water-soluble salts and their water-soluble deriv.
EXAMPLE: S-acetyl-4-(4-aminophenyl)-1-butane diol.
USE: A coupling agent. E.g. being useful for coupling two compd. with a specified functional group.
PROCESS: E.g. for a compd. with an aminophenyl terminal, a corresponding nitrophenyl analog is reduced to obtain a compd. of formula (wherein R1=NH2-).
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Inventors:
DEITON TOOMASU RIADAN
DEEN AREN GOFU
DEEN AREN GOFU
Application Number:
JP2562589A
Publication Date:
January 05, 1990
Filing Date:
February 03, 1989
Export Citation:
Assignee:
XOMA CORP
International Classes:
C07D277/78; A61K39/395; C07C323/20; C07C323/22; C07C323/29; C07C323/32; C07C323/40; C07C323/50; C07C327/28; C07C327/30; C07C327/32; C07D213/71; C07D213/89; C07D235/28; G01N33/531; (IPC1-7): C07C323/22; C07C323/29; C07C323/40; C07C323/50; C07C327/28; C07C327/32; C07D213/71; C07D213/89; C07D235/28; C07D277/78
Foreign References:
| US4544755A | 1985-10-01 |
Attorney, Agent or Firm:
Kyozo Yuasa (4 outside)