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Title:
LIQUID DOSAGE FORM OF ACID-LABILE DRUG
Document Type and Number:
Japanese Patent JP2012021008
Kind Code:
A
Abstract:

To provide a liquid composition of an acid-labile drug.

The liquid composition includes: micro-granules comprising an acid-labile drug coated with an enteric coating and a liquid vehicle having a pH less than 6.0. The components of the composition are separately provided in the form of kits. Proton pump inhibitors, in particular Lansoprazole (R), are referred to as the acid-labile drugs.


Inventors:
TANEJA RAJNEESH
Application Number:
JP2011179648A
Publication Date:
February 02, 2012
Filing Date:
August 19, 2011
Export Citation:
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Assignee:
ABBOTT LAB
International Classes:
A61K31/4439; C07D401/12; A61K9/00; A61K9/08; A61K9/10; A61K9/14; A61K9/26; A61K9/50; A61K9/58; A61P1/04; A61P43/00
Domestic Patent References:
JPH1143429A1999-02-16
JPH06502194A1994-03-10
JPH08509493A1996-10-08
JPH11501951A1999-02-16
JPS63310832A1988-12-19
JPS63310832A1988-12-19
JPH08509493A1996-10-08
JPH11501951A1999-02-16
JP2000281564A2000-10-10
JPH06319496A1994-11-22
JP2002501734A2002-01-22
Other References:
JPN6013034899; Chun AH et al.: 'Lansoprazole: administration of the contents of a capsule dosage formulation through a nasogastric t' Clin Ther. Vol.18 No.5, 199610, pp.833-842
JPN6013034901; 河田  啓暉ら: '重症心身障害児における胃食道逆流症(GER)の原因,' 医学のあゆみ Vol.165 No.12, 19930619, p.859
JPN6013034900; '第3章 ドラッグデリバリーシステムの開発, 1 コントロールリリースド製剤, 1.1 経口投与型速溶製剤' 新・ドラッグデリバリーシステム , 20000131, pp.67-76, 株式会社シーエムシー
Attorney, Agent or Firm:
Yoshio Kawaguchi
Chihiro Watanabe
Katsuma Osaki