Title:
長期作用型注射用製剤
Document Type and Number:
Japanese Patent JP5132560
Kind Code:
B2
Abstract:
The application relates to long acting injectable (LAI) formulations for combating ectoparasites and endoparasites in mammals. In particular, this invention provides for a LAI formulation comprising a subcutaneously volatile solvent, a biologically acceptable polymer, a bioactive agent and optionally one or more anti-ectoparasitically or anti-endoparasitically acceptable additive or excipient. Surprisingly, the liquid long acting injectable formulations of the invention solve the problems associated with previous injectable formulations by having long term stability, being able to accommodate smaller needle diameters and achieving long acting effects in the control of pests in a mammal. The unique formulations of the invention also allow for combating ectoparasites and endoparasites which have become resistant to macrolide antibiotics.
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Inventors:
Sol Mark Dee.
Hanson Peter
Kumar Christian
Teji Crocodile-Motwani Monica
Hanson Peter
Kumar Christian
Teji Crocodile-Motwani Monica
Application Number:
JP2008527182A
Publication Date:
January 30, 2013
Filing Date:
August 18, 2006
Export Citation:
Assignee:
MERIAL LIMITED
International Classes:
A61K47/34; A01N25/02; A01N43/22; A61K9/08; A61K31/365; A61K47/10; A61K47/14; A61K47/22; A61P33/00
Domestic Patent References:
| JP59205321A | ||||
| JP2002506797A | ||||
| JP2002506819A |
Attorney, Agent or Firm:
Masaki Hirota