Title:
ネイキッドＤＮＡ遺伝子療法のための凍結乾燥した薬剤学的組成物
Document Type and Number:
Japanese Patent JP7212230
Kind Code:
B2
Abstract:
The present invention provides a novel lyophilized pharmaceutical composition that maintains the stability of a DNA plasmid while forming a uniform and elegant cake during lyophilization. The novel lyophilization formulation further allows uniform reconstitution of the DNA plasmid in a pharmaceutically acceptable solution, enabling complete recover of the active ingredients, minimizing partial loss of potency and allowing administration of the active ingredients in an accurate and consistent manner. Additionally provided herein include methods of making the lyophilized pharmaceutical composition and methods of administering the composition for treatment of various diseases.
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Inventors:
Chan, Pyeong, Song
Application Number:
JP2021502948A
Publication Date:
January 25, 2023
Filing Date:
July 19, 2019
Export Citation:
Assignee:
Helix Miss Company, Limited
International Classes:
A61K31/7088; A61K9/08; A61K9/19; A61K47/02; A61K47/26; A61K48/00; A61P9/00; A61P9/10; A61P21/02; A61P25/02; A61P43/00
Domestic Patent References:
| JP2011516545A | ||||
| JP2001526292A |
Attorney, Agent or Firm:
Kato Kazuho
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