Title:
A MAIT Mr. cell and a manufacturing method for the same
Document Type and Number:
Japanese Patent JPWO2014069672
Kind Code:
A1
Abstract:
本発明は、ＭＡＩＴ細胞から人工多能性幹細胞を作製する方法、および、ＭＡＩＴ細胞由来の人工多能性幹細胞を提供することを課題とする。また、本発明は、人工多能性幹細胞からＭＡＩＴ様細胞を作製する方法、および、ＭＡＩＴ様細胞を提供することを課題とする。本発明によって、ＭＡＩＴ細胞に特異的なＴＣＲ遺伝子を有する人工多能性幹細胞を分化誘導してＭＡＩＴ様細胞を樹立することができる。
Inventors:
Hiroshi Wakao
Hiromi Fujita
Koshimizu right one
Yoshinori Kazunori
Hiromi Fujita
Koshimizu right one
Yoshinori Kazunori
Application Number:
JP2014544630A
Publication Date:
September 08, 2016
Filing Date:
October 30, 2013
Export Citation:
Assignee:
Daiichi Sankyo Co., Ltd.
National University Corporation Hokkaido University
National University Corporation Hokkaido University
International Classes:
C12N5/10; A61K35/12; A61K35/17; A61P31/04; A61P31/10; C12N15/09
Foreign References:
| WO2008038579A1 | 2008-04-03 | |||
| WO2010027094A1 | 2010-03-11 | |||
| WO2010134526A1 | 2010-11-25 | |||
| WO2012063817A1 | 2012-05-18 |
Other References:
LE BOURHIS, L., ET AL.: "Antimicrobial activity of mucosal-associated invariant T cells", NAT. IMMUNOL., vol. 11(8), JPN6014000784, August 2010 (2010-08-01), pages 701 - 708, ISSN: 0003554223
所和美ら: "薬効薬理試験の試験計画書 −信頼性の観点から−", JPN. PHARMACOL. THER.（薬理と治療）, vol. 31(3), JPN6014000798, 2003, pages 196 - 200, ISSN: 0003554228
山本恵司: "安全性薬理試験", 日薬理誌（FOLIA PHARMACOL. JPN.）, vol. 130, JPN6014000799, 2007, pages 299 - 303, ISSN: 0003554229
LE BOURHIS, L., ET AL.: "Mucosal-associated invariant T cells: unconventional development and function", TRENDS IN IMMUNOLOGY, vol. 32(5), JPN6014000788, May 2011 (2011-05-01), pages 212 - 218, ISSN: 0003554224
三宅幸子: "MAIT細胞と自己免疫疾患", 最新医学, vol. 66(12), JPN6014000789, 10 December 2011 (2011-12-10), pages 2736 - 2740, ISSN: 0003554225
DUSSEAUX, M., ET AL.: "Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17 -secreting T cells", BLOOD, vol. 117(4), JPN6014000792, January 2011 (2011-01-01), pages 1250 - 1259, XP055243699, ISSN: 0003554226, DOI: 10.1182/blood-2010-08-
NISHIMURA, K., ET AL.: "Development of Defective and Persistent Sendai Virus Vector; A UNIQUE GENE DELIVERY/EXPRESSION SYSTE", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 286(6), JPN6014000795, 11 February 2011 (2011-02-11), pages 4760 - 4771, ISSN: 0003554227
HAROLD AYETEY: "Therapeutic Possibilities of Induced Pluripotent Stem Cells", TRANSLATIONAL STEM CELL RESEARCH, vol. Chapter 8, JPN6017047458, 2011, pages 77 - 90, ISSN: 0003700469
所和美ら: "薬効薬理試験の試験計画書 −信頼性の観点から−", JPN. PHARMACOL. THER.（薬理と治療）, vol. 31(3), JPN6014000798, 2003, pages 196 - 200, ISSN: 0003554228
山本恵司: "安全性薬理試験", 日薬理誌（FOLIA PHARMACOL. JPN.）, vol. 130, JPN6014000799, 2007, pages 299 - 303, ISSN: 0003554229
LE BOURHIS, L., ET AL.: "Mucosal-associated invariant T cells: unconventional development and function", TRENDS IN IMMUNOLOGY, vol. 32(5), JPN6014000788, May 2011 (2011-05-01), pages 212 - 218, ISSN: 0003554224
三宅幸子: "MAIT細胞と自己免疫疾患", 最新医学, vol. 66(12), JPN6014000789, 10 December 2011 (2011-12-10), pages 2736 - 2740, ISSN: 0003554225
DUSSEAUX, M., ET AL.: "Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17 -secreting T cells", BLOOD, vol. 117(4), JPN6014000792, January 2011 (2011-01-01), pages 1250 - 1259, XP055243699, ISSN: 0003554226, DOI: 10.1182/blood-2010-08-
NISHIMURA, K., ET AL.: "Development of Defective and Persistent Sendai Virus Vector; A UNIQUE GENE DELIVERY/EXPRESSION SYSTE", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 286(6), JPN6014000795, 11 February 2011 (2011-02-11), pages 4760 - 4771, ISSN: 0003554227
HAROLD AYETEY: "Therapeutic Possibilities of Induced Pluripotent Stem Cells", TRANSLATIONAL STEM CELL RESEARCH, vol. Chapter 8, JPN6017047458, 2011, pages 77 - 90, ISSN: 0003700469
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto
Mitsutoshi Nakamura
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto
Mitsutoshi Nakamura