Title:
マラリア用ワクチン
Document Type and Number:
Japanese Patent JP2011507816
Kind Code:
A
Abstract:
The present invention relates to a component for a malaria vaccine comprising: a) an immunogenic particle RTS, S and/or b) an immunogenic particle derived from the CS protein of one or more P. vivax strains and S antigen from Hepatitis B and optionally unfused S antigen, or c) an immunogenic particle comprising RTS, CSV-S and optionally unfused S antigen, and d) a stabilizing agent comprising a stabilizing agent with at least one thiol functional group, or mixtures thereof. Methods for preparing the component, its use in medicine, particularly in the prevention of malarial infections, compositions/vaccines containing the component and use of the latter, particularly in therapy are also disclosed.
Inventors:
Le Moine, Dominique, Ingrid
Waterers, florance, emily, jeanne, francoise
Waterers, florance, emily, jeanne, francoise
Application Number:
JP2010538733A
Publication Date:
March 10, 2011
Filing Date:
December 18, 2008
Export Citation:
Assignee:
GlaxoSmithKline Biologicals Society Anonymous
International Classes:
A61K39/015; A61K9/107; A61K9/127; A61K9/19; A61K47/02; A61K47/20; A61K47/42; A61P33/06; A61P37/04; C12N15/09
Domestic Patent References:
| JP2000517295A | 2000-12-26 | |||
| JP2007512312A | 2007-05-17 | |||
| JP2002504085A | 2002-02-05 |
Foreign References:
| WO2007003384A1 | 2007-01-11 | |||
| WO2005075504A1 | 2005-08-18 |
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka