Title:
MANUFACTURE OF QUINOLINE, NAPHTHYRIDINE AND OTHER NITROGEN-BI-HETEROCYCLIC COMPOUND
Document Type and Number:
Japanese Patent JPS5758668
Kind Code:
A
Abstract:
A method for the preparation of nitrogen bi-heterocyclic compounds is disclosed involving the saponification of a compound of the formula (II) wherein R, E, D, B, A, and R' have the previously assigned significance which comprises saponifying the same by contacting it with at least a stoichiometric amount of water followed by decarboxylation. The carboxylic acid esters can be those formed by cyclization of dicarboxylic acid esters such as alpha-picolylaminomethylenemalonic acid diethyl ester.
Inventors:
KURAUSUUDEIITAA SHIYUTEFUEN
Application Number:
JP11652681A
Publication Date:
April 08, 1982
Filing Date:
July 27, 1981
Export Citation:
Assignee:
DYNAMIT NOBEL AG
International Classes:
C07D215/233; C07D215/48; C07D471/04; C07D215/22; (IPC1-7): C07D215/20; C07D215/48; C07D471/04