Title:
医薬組成物の製造方法及び医薬品混合装置
Document Type and Number:
Japanese Patent JP4974201
Kind Code:
B2
Abstract:
A change in the surface properties of apparatus for pharmaceutical preparation results from steam sterilisation. This change may be avoided by the use of apparatus with more hydrophilic post-sterilisation surfaces, e.g. those of gold. Hence there is provided a process for the preparation of a mixture comprising a discontinuous phase in a continuous phase which comprises using a mixing apparatus having a non-porous mixing surface which is repellant to the discontinuous phase and/or attractive to the continuous phase when the continuous phase is liquid or which is attractive to the discontinuous phase when the continuous phase is gaseous, whereby to improve the efficacy of the preparation of said mixture and/or to reduce physical degradation of said mixing surface, said surface if hydrophilic being more hydrophilic after sterilisation than is stainless steel and if hydrophobic being more hydrophobic after sterilisation than is stainless steel.
Inventors:
Omutbait, training
Honneld, Anne-Christine
Honneld, Anne-Christine
Application Number:
JP2000566009A
Publication Date:
July 11, 2012
Filing Date:
August 18, 1999
Export Citation:
Assignee:
GE Healthcare Aksuye Sersukapu
International Classes:
A61J3/00; A61L2/06; B01F23/10
Domestic Patent References:
| JP10505900A | ||||
| JP10137577A | ||||
| JP8141378A | ||||
| JP63501723A | ||||
| JP8505312A | ||||
| JP58087296A |
Foreign References:
| US2592876 |
Attorney, Agent or Firm:
Arakawa Satoshi
Kenichi Matsumoto
Kenichi Matsumoto