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Patent Searching and Data


Title:
発酵による精密化学物質の製造方法
Document Type and Number:
Japanese Patent JP2007514439
Kind Code:
A
Abstract:
The present invention features methods of increasing the production of a fine chemical, e.g., lysine from a microorganism, e.g., Corynebacterium by way of deregulating an enzyme encoding gene, i. e., glycerol kinase. In a preferred embodiment, the invention provides methods of increasing the production of lysine in Corynebacterium glutamicum by way of increasing the expression of glycerol kinase activity. The invention also provides a novel process for the production of lysine by way of regulating carbon flux towards oxaloacetate (OAA). In a preferred embodiment, the invention provides methods for the production of lysine by way of utilizing fructose or sucrose as a carbon source.

Inventors:
Zelder, oscar
Croplogge, Corinna
Schrader, Hartwig
Haefner, stephan
Craiger, Burghard
Kiefer, Patrick
Heinzul, Elmer
Wittmann, Christoph
Application Number:
JP2006544606A
Publication Date:
June 07, 2007
Filing Date:
December 17, 2004
Export Citation:
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Assignee:
BASF Aktiengesellschaft
International Classes:
C12N1/21; C12N15/09; C12P13/08; C12P
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita