Title:
早発的染色体凝縮を誘導するための材料及び方法
Document Type and Number:
Japanese Patent JP2004529628
Kind Code:
A
Abstract:
The present invention provides a simple and rapid method to study chromosome aberrations using unstimulated cells. Premature chromosome condensation is induced by incubating unstimulated cells in the presence of a mitosis-enhancing factor. The condensed chromosomes produced by the present methods can be used in numerous forms of cytogenetic analysis, in particular, with in situ hybridization probes and chromosome painting. This technique can be applied to biological dosimetry of radiation exposures involving uniform whole-body low-linear energy transfer exposures.
Inventors:
Prasana, Patajasie. S.
Blakely, William, F.
Blakely, William, F.
Application Number:
JP2002568699A
Publication Date:
September 30, 2004
Filing Date:
February 28, 2002
Export Citation:
Assignee:
The Henry M. Jackson Foundation
International Classes:
G01N33/53; C12N5/07; C12N15/09; C12Q1/02; C12Q1/48; C12Q1/68; G01N33/566; G01N33/68; C12Q1/6841; C12R1/91; (IPC1-7): C12N5/06; C12Q1/02; C12Q1/68; G01N33/53; G01N33/566
Attorney, Agent or Firm:
Yuichi Yamada
Yasuhito Suzuki
Yasuhito Suzuki