Title:
Medical treatment of atonal homolog 1 (ATOH1) associated diseases by prevention of the natural antisense transcript to ATOH1
Document Type and Number:
Japanese Patent JP5973996
Kind Code:
B2
Abstract:
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Atonal homolog 1 (ATOH1), in particular, by targeting natural antisense polynucleotides of Atonal homolog 1 (ATOH1). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of ATOH1.
Inventors:
Corrado, Joseph
Corcowa Sherman, Olga
Corcowa Sherman, Olga
Application Number:
JP2013512184A
Publication Date:
August 23, 2016
Filing Date:
May 25, 2011
Export Citation:
Assignee:
Copper RNA, Inc.
International Classes:
C12N15/09; A61K31/7088; A61K31/7125; A61K48/00; A61P25/00; A61P27/16; A61P43/00; C12N15/113
Foreign References:
| WO2010040112A1 |
Other References:
J Biol Chem. 2010 Jan, Epub 2009 Oct;285(1):392-400
Attorney, Agent or Firm:
Ryoichi Takaoka