Title:
METHOD FOR FRACTIONATING CANCER STEM CELL-LIKE CELL
Document Type and Number:
Japanese Patent JP2022115448
Kind Code:
A
Abstract:
To provide a novel therapeutic method targeting a cancer stem cell-like cell, where the method is used for preventing and completely curing metastasis/recurrence of cancer.SOLUTION: Provided is a method in which a cancer stem cell-like cell is acquired from a cell population having cancer cells on the basis of an expression of neuropilin 1(NRP1) or insulin-like growth factor 1 receptor (IGF1R), an expression of FXYD domain-containing ion-transporting regulator 3 (FXYD3) is detected regarding an acquired cancer stem cell-like cell, and the cell is fractionated into a resting cancer stem cell-like cell of high FXYD3 expression and a proliferative cancer stem cell-like cell of low FXYD3 expression.SELECTED DRAWING: None
Inventors:
GOTO NORIKO
NISHIMURA TATSUNORI
LI MENGJIAO
OKAMOTO YASUSHI
NISHIMURA TATSUNORI
LI MENGJIAO
OKAMOTO YASUSHI
Application Number:
JP2021012049A
Publication Date:
August 09, 2022
Filing Date:
January 28, 2021
Export Citation:
Assignee:
UNIV KANAZAWA
International Classes:
C12N5/095; A61K39/395; A61K47/68; A61P35/00; C07K16/18; C12Q1/02; C12Q1/6851; C12Q1/686; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Hiraki International Patent Office
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