Title:
幹細胞のインビボ移動誘導方法
Document Type and Number:
Japanese Patent JP5828916
Kind Code:
B2
Abstract:
The present invention relates to an implantable composition for treating a damaged tissue and a method for inducing an in vivo migration of a cell for treatment to a damaged tissue region. The present invention treats the damaged tissue by inducing/promoting homing of a cell for tissue generation by implanting a biodegradable scaffold reacted with chemotactic factors (for example, IL-8 or MIP-3±) to a damaged location (for example, joint cartilage or skin). Thus, the composition of the present invention can not only be applied to the treatment of a damaged bone tissue, a joint cartilage, or a skin tissue more conveniently and efficiently compared to the conventional technology, but can also be used as a useful treatment supplement agent in cell treatment using allogeneic cell by enabling efficient utilization of cell resources for treatment, the cell resources which are high in scarcity.
Inventors:
Li Jinwoo
Park Min Sung
Kim Young Hee
Park Min Sung
Kim Young Hee
Application Number:
JP2013557637A
Publication Date:
December 09, 2015
Filing Date:
January 26, 2012
Export Citation:
Assignee:
Tego Science, Inc.
International Classes:
A61K38/00; A61K9/70; A61K35/28; A61K35/36; A61K47/32; A61K47/34; A61K47/42; A61L27/00; A61P17/00; A61P19/02; A61P19/08; A61P43/00
Domestic Patent References:
| JP2009517078A |
Foreign References:
| WO2010120757A1 | ||||
| WO2005074836A1 | ||||
| US20110038921 | ||||
| WO2009146456A1 | ||||
| WO2008008266A1 |
Other References:
J. Cell. Biochem., 2007, Vol.101, No.1, pp.135-146
Attorney, Agent or Firm:
Koichi Hirota
Yoshihiro Nagare
Naoko Matsuda
Yoshihiro Nagare
Naoko Matsuda
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