Title:
METHOD FOR PRODUCING ACTIVE CONSTITUENT OF PHARMACEUTICAL OR DIAGNOSTIC AGENT IN MDCK CELL SUSPENSION CULTURE
Document Type and Number:
Japanese Patent JP2011212021
Kind Code:
A
Abstract:
To provide a method for producing an active constituent of a pharmaceutical or a diagnostic agent.
In the method, (a) MDCK cells are infected with a virus and (b) the MDCK cells are cultured in a suspension culture on a commercial scale under conditions enabling the virus to multiply, wherein the culture process is carried out in a volume of at least 30 L. In the method for producing a pharmaceutical or a diagnostic agent, the active constituent is produced by the method and mixed with a suitable adjuvant, auxiliary agent, buffering agent, diluting agent or pharmaceutical carrier.
Inventors:
VORLOP JUERGEN
FRECH CHRISTIAN
LUEBBEN HOLGER
GREGERSEN JENS-PETER
FRECH CHRISTIAN
LUEBBEN HOLGER
GREGERSEN JENS-PETER
Application Number:
JP2011158481A
Publication Date:
October 27, 2011
Filing Date:
July 19, 2011
Export Citation:
Assignee:
NOVARTIS VACCINES & DIAGNOSTICS GMBH & CO KG
International Classes:
C12N7/04; C12P21/02; A61K39/12; A61K39/145; A61K39/39; A61K48/00; A61P31/12; A61P31/16; C12N5/06; C12N5/10; C12N7/00; C12N7/02; C12N15/867; A61K39/00
Domestic Patent References:
| JP2000507448A | 2000-06-20 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita
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