Title:
MONOCLONAL ANTIBODY
Document Type and Number:
Japanese Patent JPH07179497
Kind Code:
A
Abstract:
PURPOSE: To obtain a monoclonal antibody against a ganglioside containing de-N-acetylsialic acid.
CONSTITUTION: This-monoclonal antibody is prepared by chemically synthesizing de-N-acetyl GM2 which is a ganglioside containing de-N-acetylsialic acid (Japanese Patent Application Hei 4-173148), immunizing a mouse with the synthesized de-N-acetyl GM2, extracting the spleen cell from the immunized mouse, fusing with a myeloma cell to obtain a hybridoma, cloning the prepared hybridoma to establish a hybridoma DM2-1 (deposited in the National Institute of Bioscience and Human Technology as FERM P-13960) and using the hybridoma DM2-1 for the preparation of the monoclonal antibody.
Inventors:
YAMAKAWA MIDORI
SUDA ISAO
FUJITA HIDEJI
SUDA ISAO
FUJITA HIDEJI
Application Number:
JP29486893A
Publication Date:
July 18, 1995
Filing Date:
November 25, 1993
Export Citation:
Assignee:
KANTO ISHI PHARMA CO LTD
International Classes:
G01N33/53; A61K39/395; C07K16/00; C07K16/30; C07K19/00; C12N15/02; C12P21/08; G01N33/577; C12R1/91; (IPC1-7): C07K16/30; A61K39/395; C12P21/08; G01N33/53; G01N33/577
Attorney, Agent or Firm:
Kenji Yoshida