Multi-substitution aromatic compounds as serine protease inhibitor

Title:

Multi-substitution aromatic compounds as serine protease inhibitor

Document Type and Number:

Japanese Patent JP2016513714

Kind Code:

A

Abstract:

特に、カリクレインを阻害するのに有用な多置換芳香族化合物が提供され、化合物は、置換ピラゾリル又は置換トリアゾリルを含む。更に、医薬組成物が提供される。更に、特定の疾患又は障害の治療方法及び予防方法が提供され、疾患又は障害は、カリクレインの阻害によって治療又は予防が可能である。【選択図】なし

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Inventors:

Short, kevin, michael
Pham, Sun, Min
Williams, David, Charles
Kita, David, Ben

Application Number:

JP2016502572A

Publication Date:

May 16, 2016

Filing Date:

March 17, 2014

Export Citation:

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Assignee:

Verseon Corporation

International Classes:

A61K31/415; A61K9/08; A61K31/4439; A61K31/444; A61K31/501; A61K31/506; A61K31/5377; A61P1/04; A61P3/10; A61P7/02; A61P9/10; A61P11/00; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P35/00; A61P37/08; A61P43/00; C07D401/04; C07D405/14; C07D409/14

Domestic Patent References:

JP2011520967A	2011-07-21
JP2006511608A	2006-04-06

Foreign References:

WO2011126903A2

2011-10-13

Attorney, Agent or Firm:

Seiji Ohno
Reiko Tanaka
Yuko Matsuniya
Ken Kitano
Umeda Shinsuke
Hiroshi Morita
Tsukuda Seigen

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