Title:
MUTILIN DERIVATIVE CONTAINING HETEROAROMATIC RING CARBOXYLIC ACID STRUCTURE AT 14-POSITION SUBSTITUENT
Document Type and Number:
Japanese Patent JP2010100582
Kind Code:
A
Abstract:
To provide a 12-position substituted derivative that is a new analog of mutilin which exhibits a strong and broad antibacterial action against Gram-positive and Gram-negative bacteria including various resistant bacteria and is expected to be useful as an anti-infective agent and a production intermediate thereof.
The new mutilin derivative is a compound represented by general formula (1) and (2).
Inventors:
TAKADOI MASANORI
Application Number:
JP2008274936A
Publication Date:
May 06, 2010
Filing Date:
October 24, 2008
Export Citation:
Assignee:
KYORIN SEIYAKU KK
International Classes:
C07D401/04; A61P31/04; A61K31/4709
Domestic Patent References:
| JP2003529593A | 2003-10-07 | |||
| JP2006306727A | 2006-11-09 | |||
| JP2008534443A | 2008-08-28 | |||
| JP2008201675A | 2008-09-04 |
Foreign References:
| WO2006070671A1 | 2006-07-06 | |||
| WO2007062335A2 | 2007-05-31 | |||
| WO2008143343A1 | 2008-11-27 |