Title:
MICROCAPILLARY ARRAY, ITS PRODUCTION, AND MATERIAL INJECTION DEVICE
Document Type and Number:
Japanese Patent JP3035608
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a microcapillary array capable of individually and properly manipulating cells, therefore useful in e.g. gene transfer operations, so designed that a plurality of hollow capillaries each consisting of a thin filmy material and having a specified outer diameter are penetrated through a substrate and projected from one surface of the substrate so as to represent a two-dimensional array fashion.
SOLUTION: This microcapillary array is so designed that a plurality of hollow capillaries 16 each consisting of a thin filmy material such as silicon oxide or silicon nitride and having an outer diameter of 2-10 μm are penetrated through a substrate such as a silicon substrate and projected from one surface of the substrate so as to represent a two-dimensional array fashion; wherein the respective tips of these hollow capillaries 16 communicate with the outside at the respective parts other than the forefront tips. Furthermore, it is preferable that each of the microcapillaries is made by the following procedure: a fine hole is bored from one surface of the substrate inward, a thin film is formed on the inner wall of the hole, the substrate is then etched from the opposite surface to expose the hollow structure consisting of the thin film formed on the inner wall of the hole, and the tip of the hollow structure is opened.
Inventors:
Yuji Kikuchi
full teaching
Hiroshi Toshiyoshi
Hiroyuki Fujita
full teaching
Hiroshi Toshiyoshi
Hiroyuki Fujita
Application Number:
JP19393198A
Publication Date:
April 24, 2000
Filing Date:
July 09, 1998
Export Citation:
Assignee:
Director, Food Research Institute, Ministry of Agriculture, Forestry and Fisheries
International Classes:
G01N1/00; C12M1/00; C12N5/10; C12N15/09; (IPC1-7): C12M1/00; C12N5/10; C12N15/09; G01N1/00
Domestic Patent References:
| JP1112976A |
Other References:
【文献】横田 崇、新井賢一編集、実験医学別冊バイオマニュアルシリーズ4 遺伝子導入と発現・解析法、株式会社 羊土社、1994年4月20日、p.36
Attorney, Agent or Firm:
Yusuke Hiraki (1 person outside)