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Title:
MELAMINE PRODUCTION-INHIBITING EXTERNAL AGENT
Document Type and Number:
Japanese Patent JPH0648935
Kind Code:
A
Abstract:

PURPOSE: To provide the skin external agent exhibiting a good percutaneous absorbing property, effectively inhibiting the coloration.decomposition of skin with light or heat, having an excellent melanogenesis-inhibiting action, and useful for preventing and also treating stains and ephelis.

CONSTITUTION: The melanogenesis-inhibiting external agent contains at least one selected from a group of iminodibenzyl compounds, dibenzocycloheptadiene compounds and ketotifen fumarate as an active ingredient in an amount of 0.00015-10wt.%, preferably 0.01-5wt.%. The addition of a whitening agent selected from a group of kojic acid, ascorbic acid, hydroquinone, liquiritin or their derivatives and a placenta extract gives a synergistic effect. The addition of an UV light absorbent (e.g. a dibenzoylmethane UV light absorbent or a plant extract having an absorption spectrum in a region ranging from the UV-B region to the UV-A region) and/or an antioxidant (e.g. a tocopherol compound) permits to effectively inhibit the coloration.decomposition of skin with light and heat.


Inventors:
IWANAGA ATSUFUMI
Application Number:
JP12979593A
Publication Date:
February 22, 1994
Filing Date:
May 31, 1993
Export Citation:
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Assignee:
SANSHO SEIYAKU KK
International Classes:
A61K8/30; A61K8/00; A61K8/31; A61K8/33; A61K8/34; A61K8/35; A61K8/36; A61K8/362; A61K8/368; A61K8/49; A61K8/60; A61K8/97; A61K8/98; A61Q17/04; A61Q19/00; A61Q19/02; (IPC1-7): A61K7/48; A61K7/00; A61K7/42
Attorney, Agent or Firm:
Yukio Shoko



 
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